96.00 USD – 475.20 USD
Thrombopoietin is a glycoprotein hormone produced mainly by the liver and the kidney that regulates the production of platelets by the bone marrow. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. It stimulates the production and differentiation of megakaryocytes, the bone marrow cells that fragment into large numbers of platelets.
polyhistidine tag at the N-terminus
<0.01 EU per 1 μg of the protein by the LAL method.
Measure by its ability to induce proliferation in MO7e cells. The ED50 for this effect is <2 ng/mL. The specific activity of recombinant human TPO is > 5 x 105 IU/mg.
>95% as determined by SDS-PAGE. Ni-NTA chromatography
The protein was lyophilized from a solution containing 1X PBS, pH 7.4.
It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
Lyophilized protein should be stored at -20°C. Upon reconstitution, protein aliquots should be stored at -20°C or -80°C.
Please use within two weeks after protein reconstitution.
5 μg, 20 μg, 100 µg