The JES5-2A5 antibody is specific for mouse IL-10. IL-10 has numerous biological activities including the ability to inhibit both the synthesis of Th1 cytokines and proliferation of T cells. In the mouse, IL-10 is produced by phagocytic cells, conventional dendritic, cells, T cells, B cells, and NK cells. The JES5-2A5 antibody is a neutralizing antibody.
||In Vivo Ready™ Anti-Mouse IL-10 (JES5-2A5)
||Rat IgG1, kappa
||In Vivo Ready™
||Abrams JS, Roncarolo MG, Yssel H, Andersson U, Gleich GJ, Silver, JE. 1992. Immunol Rev. 127:5-24.
Sander B, Hoiden I, Andersson U, Moller E, Abrams JS. 1993. J Immunol Methods. 166(2):201-214.
Marchant A, Bruyns C, Vandenabeele P, Ducarme M, Gérard C, Delvaux A, De Groote D, Abramowicz D, Velu T, Goldman M. 1994. Eur J Immunol. 24(5):1167-1171.
Asseman C, Mauze S, Leach MW, Coffman RL, Powrie F. 1999. J Exp Med. 190:995-1004.
Application Key:FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.
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