The 61D3 antibody is specific for human CD14, a 53-55 kDa GPI-anchored glycoprotein. CD14 is highly expressed on monocytes and to a lesser extent on interfollicular macrophages, and some dendritic cells. Together with LPS-Binding Protein (LBP), CD14 binds to and mediates the innate immune response to bacterial lipopolysaccharide (LPS).
||FITC Anti-Human CD14 (61D3)
||Mouse IgG1, kappa
||Hogg N, Horton MA. 1987. In: McMichael AJ, Beverley PCL, Cobbold S, et al., eds. Leucocyte Typing III: White Cell Differentiation Antigens. New York, NY: Oxford University Press; 576-602.
Haziot A, Chen S, Ferrero E, Low MG, Silber R, Goyert SM. 1988. J Immunol. 141:547-552.
Application Key:FC = Flow Cytometry; FA = Functional Assays; ELISA = Enzyme-Linked Immunosorbent Assay; ICC = Immunocytochemistry; IF = Immunofluorescence Microscopy; IHC = Immunohistochemistry; IHC-F = Immunohistochemistry, Frozen Tissue; IHC-P = Immunohistochemistry, Paraffin-Embedded Tissue; IP = Immunoprecipitation; WB = Western Blot; EM = Electron Microscopy
*Tonbo Biosciences tests all antibodies by flow cytometry. Citations are provided as a resource for additional applications that have not been validated by Tonbo Biosciences. Please choose the appropriate format for each application and consult the Materials and Methods section for additional details about the use of any product in these publications.
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