Description
Catalog No. T0684 CAS 36791-04-5 Synonyms: ICN-1229, NSC-163039, Tribavirin, RTCA
Ribavirin is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses.
Biological Activity:
| Product Description:
Ribavirin is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses. |
| Receptor:
ADK; IMPDH1; RNA polymerase; |
Chemical Information:
| Molecular Weight | 244.20 |
| Formula | C8H12N4O5 |
| CAS Number | 36791-04-5 |
| Solubility |
DMSO: 24.4 mg/mL (100 mM) water: 24.4 mg/mL (100 mM) ( < 1 mg/ml refers to the product slightly soluble or insoluble ) |
| Storage | store at -80°C |
| Remark | For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month. |
Technical Support
Answers to questions you may have can be found in the inhibitor handling instructions. Topics include how to prepare stock solutions, how to store Products, and issues that need special attention for cell-based assays and animal experiments.
Reference
- 1. Feld JJ, et al. Nature, 2005, 436(7053), 967-972.
- 2. Crotty S, et al. Nat Med, 2000, 6(12), 1375-1379.
- 3. Crotty S, et al. Proc Natl Acad Sci U S A, 2001, 98(12), 6895-6900.
- 4. Ning Q, et al. J Immunol, 1998, 160(7), 3487-3493.
- 5. Graci JD et al. Rev Med Virol, 2006, 16(1), 37-48.
- 6. Refaat B, et al. The effects of pegylated interferon-α and ribavirin on liver and serum concentrations of activin-A and follistatin in normal Wistar rat: a preliminary report. BMC Res Notes. 2015 Jun 26;8:265
- 7. Abdel-Hamid NM, et al. Synergistic Effects of Jerusalem Artichoke in Combination with Pegylated Interferon Alfa-2a and Ribavirin Against Hepatic Fibrosis in Rats. Asian Pac J Cancer Prev. 2016;17(4):1979-85.
Additional information
| Size | 100 mg, 200 mg, 1 mL * 10 mM (in DMSO) |
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