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BioMab Circulating Tumour Cells (CTC) Enrichment Kit

Our CTC enrichment kit is the most sensitive platform with high specificity – EpCAM antibody with the highest binding affinity (Kd < 10-12).

Description

Circulating Tumour Cells (CTC)

CTC is rare (1 in 109 cells) – detecting CTCs with high sensitivity and specificity is a major challenge. Our CTC enrichment kit is the most sensitive platform with high specificity – EpCAM antibody with the highest binding affinity (Kd < 10-12).

  • It can be used with liquid Biopsy – detecting cancers through a simple blood draw
  •  Clinical data in breast, colorectal, gastric, head & neck, non-small cell lung cancers across 4 notable teaching hospitals in Taiwan.
  •  2 paper citations by CellSearch Inventor (Professor Leon Terstappen)
  • —  Detects CTCs in >95% of patients enrolled (n > 125)
  • —  Capturing live CTCs for culturing (success rate reaching ~96%, n = 50)
  • —  Successfully performed NGS on CTCs captured from patients
  • —  Can capture CTC with low EpCAM Expressions (e.g., CTCs with EMT, MDA-MB-231)

CTC Competitor Comparison

Company Technology Platform Sensitivity Specificity Culturing & Sequencing Capturing Clusters Pricing
BioMab Anti-EpCAM Antibody (EpCAM Ab, Kd < 10^-12)
conjugated with magnetic beads

 

Anti-EpCAM Antibody highest binding affinity in
the world

High High Low
Competitor A Microfluidics coated with antibodies Low Low X X Low
Competitor B Anti-EpCAM antibody conjugated with magnetic beads Low High X X High
Competitor C Microfluidics plus anti-EpCAM antibody conjugated
with magnetic beads
Low High X X High
Competitor D Microfluidics based on cell size High Low High
Competitor E Antibody and FISH probes Low High X Low