Immunology and inflammation
Immunology is an important discipline that makes us understand the element of our immune system. It begins with Edward Jenner’s discovery of the world’s first smallpox vaccine in the 1800s. Indubitably, people praised him as a “father of immunology.” Major advances made by Louis Pasteur and many other scientists further our understanding in cellular components of the immune system such as T or B cells. The revolution of biological technologies such as flow cytometry and genetic engineering in the 1970s, enabled scientists to profoundly study the molecular level in physiological and pathological processes of the immune system.
Inflammation (swelling) is a defense mechanism found in both physiological and pathological processes. It is a process by which our body’s immune cells protect us from infection and injury from invaders such as bacteria and virus. Inflammation is a natural part of the wound healing process and begins right after the injury. Immune cells are recruited to the site of injury to remove damaged cells and pathogens, preventing further infection. Inflammation is also involved in many abnormalities such as hypersensitivity, autoimmune diseases, or cancer, in which chronic inflammation results in DNA damage. Cancer immunotherapy is one of the leading therapeutic strategies that have confirmed their potential in many relapse cancer patients by using cell therapy (e.g. CAR-T cells, NK/T cells), cancer vaccines, or monoclonal antibodies targeted therapy.
Atlantis Bioscience is committed to provide the highest quality reagents for immunology research.
Try our Atlantis NK activation and expansion kit for robust NK cells activation and expansion. Optimize and differentiate your immune cell culture with the addition of bioactive recombinant proteins. Our portfolio includes cytokines, chemokines, growth factors and GMP-grade proteins. Choose from an expansive collection of fluorochrome-conjugated antibodies for flow cytometry to identify and characterize immune cells. Explore our In Vivo Ready™ Reagents widely used for activation in solid phase/plate-bound assays, neutralization of receptor-ligand interactions and modulation of functional activity in vivo.
Check out the inflammation services from CrownBio, which provides well-characterized in vivo models for inflammatory and autoimmune disease drug development. CrownBio also provides a range of validated genomic and proteomic biomarker assays to inform on oncology and inflammation, enabling detection and discovery of biomarkers. Services include ELISA-based cytokine and chemokine profiling, multi-parametric flow cytometry for immunophenotyping, genomic analysis, rare cell analysis and many more.