FOBI is a bioimaging instrument which images and analyzes fluorescence signal from fluorescence labeled organism.
FOBI uses light source and filter that are optimized for In Vivo imaging to distinguish background and signal without preprocessing.
It is possible to take an image of tumorization animal using stable expressed GFP tumor cell line.
FOBI can check the antitumor activity without sacrificing the animals by intensity measuring.
FOBI can determine the location and extent of the cancer metastasis by tracking the fluorescence signal.
FOBI can confirm survival and location of target cell that made by variety purposes.
There are several problems with introduction of the fluorescence gene using a viral,
stem cells and immune cells can check In Vivo after staining the cells using a fluorescent dye.
The results of In vivo imaging data can confirm once again by Ex vivo imaging.
Fluorescence signal can expressed continuously after animal was sacrificed. It is possible to quantify the fluorescence image again thru obtain the separation.
Ex vivo data that obtained as above can be good evidence and increase the reliability of the test.
FOBI can take imaging and quantitative analysis in plant leaves.
It’s very hard thing because Chlorophyll’s auto fluorescence.
FOBI’s color camera can taking not only GFP’s green fluorescence but also red fluorescence. So you can also check the plants’ health condition.
You can check both of GFP analysis and health condition at one leaf.
FOBI can take imaging at seed and callus.
You can check the function thru whole period of growth and regeneration.