Interleukin-4 (rHu IL-4), produced primarily by CD4(+) T cells is an immunomodulatory cytokine, which can inhibit the growth of tumor cells.
IL-4 has been known as a Th2 cytokine and can act on B cells, T cells, and monocytes. IL-4 exhibits antitumor activity in rodent experimental gliomas, which is likely mediated by the actions of IL-4 on a variety of immune cells present in and around the tumor masses. rHu IL-4 produced in E. coli is a single, non-glycosylated polypeptide chain that contains 130 amino acids and has a molecular mass of 15 kDa.
Features and Specifications:
Akron’s cGMP Cytokines are manufactured, tested and released in compliance with relevant cGMP guidelines. USP Chapter ‹1043› “Ancillary materials for cell, gene and tissue-engineered products” has been followed in the design of these products.
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